IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28357
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
ELISA, Flow Cytometry, Functional
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Human IgG2 Clone # nemolizumab
Concentration
LYOPH mg/ml
Product Specifications
Immunogen
IL-31Ra
Reactivity Notes
Predicted species reactivity: Cynomolgus
Clonality
Monoclonal
Host
Human
Isotype
IgG2
Endotoxin Level
< 0.001EU/ug,determined by LAL method.
Description
Expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
Also known as 'nemolizumab'.
IgG2SA is human IgG2 with S378A mutation.
Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Also known as 'nemolizumab'.
IgG2SA is human IgG2 with S378A mutation.
Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Scientific Data Images for IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA
Functional: IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA[NBP3-28357] -
IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA P-STAT3 Assay was evaluated using Du145. The IC50 was approximately 0.1068 ug/ml.
Functional: IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA[NBP3-28357] -
IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA Activation inhibition was evaluated using Hacat. The max induction fold was approximately 1.86.
ELISA: IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA[NBP3-28357] -
Immobilized human IL31R His at 2 ug/mL can bind IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA, EC50=0.0153 ug/mL.Applications for IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA
Application
Recommended Usage
ELISA
Optimal dilutions of this antibody should be experimentally determined.
Flow Cytometry
Optimal dilutions of this antibody should be experimentally determined.
Functional
Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A purified
Reconstitution
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
Formulation
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH mg/ml
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: IL-31RA
Long Name
Interleukin 31 Receptor A
Alternate Names
CRL3, GLM-R, IL-31 RA, IL31RA
Gene Symbol
IL31RA
UniProt
Additional IL-31RA Products
Product Documents for IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA
Product Specific Notices for IL-31RA Antibody (nemolizumab) - Humanized, IgG2SA
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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