IL18R1 Antibody (B-E43) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14586

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # B-E43

Format

Azide and BSA Free

Concentration

1 mg/ml

View all IL18R1 Antibodies »

Product Specifications

Immunogen

Recombinant human IL18R1

Specificity

recognizes IL18R1, a 63 kDa protein. Cross-reacts with mouse CDw218a protein in cytometry.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Stable at 4C for 12 months.

Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells

Scientific Data Images for IL18R1 Antibody (B-E43) - Azide and BSA Free

Flow Cytometry: IL18R1 Antibody (B-E43) - Azide and BSA Free [NBP3-14586]

Flow Cytometry: IL18R1 Antibody (B-E43) - Azide and BSA Free [NBP3-14586]

Flow Cytometry: IL18R1 Antibody (B-E43) [NBP3-14586] - A typical staining pattern with B-E43 monoclonal antibody on U937 cell line.

Applications for IL18R1 Antibody (B-E43) - Azide and BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Biological Activity: Inhibits human IFN-gamma secretion induced by IL-18 stimulated cells

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS. Sterile-filtered through 0.22 um.

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IL18R1

IL-18 receptor is composed of an alpha and a beta subunit that combine to form a high affinity receptor for IL-18. IL-18 receptor alpha chain, also known as CDw218a, is a 75-80 kD type I transmembrane protein. It is expressed on NK cells, neutrophils, endothelial cells, and subsets of T and B cells. The expression of CDw218a on lymphocytes is upregulated after activation. The interaction of IL-18 and IL-18 receptor has been reported to be implicated in promotion of Th1 cytokine production and atherogenesis. The H44 antibody is specific for IL-18 receptor alpha chain and has been reported to block IL-18 binding to the receptor and to be useful for the identification of IL-18 receptor by flow cytometry and IHC.

Alternate Names

CD218 antigen-like family member A, CD218a, CD218a antigen, CDw218a, cytokine receptor, IL-18R1, IL-18R-1, IL1R-rp, IL1RRPIL1 receptor-related protein, IL-1RrpIL18RA, interleukin 18 receptor 1, interleukin-18 receptor 1

Gene Symbol

IL18R1

Additional IL18R1 Products

Product Documents for IL18R1 Antibody (B-E43) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IL18R1 Antibody (B-E43) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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