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ILT5/CD85a/LILRB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24915

Novus Biologicals, part of Bio-Techne
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NBP3-24915

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein ILT5/CD85a/LILRB3 using the following amino acid sequence: CHYYSSAGWSEPSDPLELVMTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ILT5/CD85a/LILRB3 Antibody

ILT5/CD85a/LILRB3 Antibody Immunocytochemistry/Immunofluorescence: ILT5/CD85a/LILRB3 Antibody [NBP3-24915]

Immunocytochemistry/Immunofluorescence: ILT5/CD85a/LILRB3 Antibody [NBP3-24915]

Staining of human cell line HaCaT shows localization to plasma membrane.

Applications for ILT5/CD85a/LILRB3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: LILRB3/CD85a/ILT5

LILRB3 is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signaling modulators and inhibitors of cell activation. LILRB3 may act as receptor for class I MHC antigens.

Alternate Names

CD85a, ILT5, LIR3

Gene Symbol

LILRB3

Additional LILRB3/CD85a/ILT5 Products

Product Documents for ILT5/CD85a/LILRB3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ILT5/CD85a/LILRB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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