Importin-8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87878

Novus Biologicals, part of Bio-Techne
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NBP1-87878
NBP1-87878-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Importin-8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SNNGRGEDEEEEDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALITVQSRDAAWYQLLMAPLSEDQRTALQEVYTLAEHRRTVAEAKKKIEQQGGFTFENKGVLSAFNFGTVPSNN

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Importin-8 Antibody

Immunocytochemistry/ Immunofluorescence: Importin-8 Antibody [NBP1-87878]

Immunocytochemistry/ Immunofluorescence: Importin-8 Antibody [NBP1-87878]

Immunocytochemistry/Immunofluorescence: Importin-8 Antibody [NBP1-87878] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
Immunohistochemistry-Paraffin: Importin-8 Antibody [NBP1-87878]

Immunohistochemistry-Paraffin: Importin-8 Antibody [NBP1-87878]

Immunohistochemistry-Paraffin: Importin-8 Antibody [NBP1-87878] - Staining of human kidney shows strong cytoplasmic positivity in subsets of cells.

Applications for Importin-8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin-8

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. [provided by RefSeq]

Alternate Names

FLJ21954, FLJ26580, IMP8, importin 8, importin-8, RAN binding protein 8, Ran-binding protein 8, RanBP8, RANBP8imp8

Gene Symbol

IPO8

Additional Importin-8 Products

Product Documents for Importin-8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Importin-8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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