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Importin alpha 3/KPNA4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31260

Novus Biologicals, part of Bio-Techne
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NBP1-31260

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human, Mouse

Predicted:

Bovine (100%), Chimpanzee (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Importin alpha 3/KPNA4. The exact sequence is proprietary.

Localization

Cytoplasm, Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

58 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Importin alpha 3/KPNA4 Antibody

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 7.5% SDS PAGE diluted at 1:1000
Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Immunocytochemistry/Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - Analysis of HeLa, using KPNA4 antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP1-31260]

Immunohistochemistry-Paraffin: Importin alpha 3/KPNA4 Antibody [NBP1-31260] - H1299 xenograft, using KPNA4 antibody at 1:500 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

Applications for Importin alpha 3/KPNA4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP1-31260 in the following applications:

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS, 1% BSA, 20% Glycerol (pH7)

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Importin alpha 3/KPNA4

The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

Long Name

Karyopherin alpha 4

Alternate Names

KPNA4, QIP12, SRP3

Entrez Gene IDs

3840 (Human)

Gene Symbol

KPNA4

UniProt

Additional Importin alpha 3/KPNA4 Products

Product Documents for Importin alpha 3/KPNA4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Importin alpha 3/KPNA4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.