Importin alpha 3/KPNA4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76300

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Importin alpha 3/KPNA4 Antibodies »

Product Summary for Importin alpha 3/KPNA4 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA4. The immunogen is located within amino acids 30 - 80 of KPNA4. Amino Acid Squence: RNVPQEDICEDS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Importin alpha 3/KPNA4 Antibody - BSA Free

Western Blot: Importin alpha 3/KPNA4 AntibodyBSA Free [NBP1-76300]

Western Blot: Importin alpha 3/KPNA4 AntibodyBSA Free [NBP1-76300]

Western Blot: Importin alpha 3/KPNA4 Antibody [NBP1-76300] - Hela cell lysate with KPNA1 antibody at 1ug/mL.
Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody - BSA Free [NBP1-76300]

Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody - BSA Free [NBP1-76300]

Immunocytochemistry/Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP1-76300] - Immunofluorescence of KPNA4 in HeLa cells with KPNA4 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody - BSA Free [NBP1-76300]

Immunocytochemistry/ Immunofluorescence: Importin alpha 3/KPNA4 Antibody - BSA Free [NBP1-76300]

Immunocytochemistry/Immunofluorescence: Importin alpha 3/KPNA4 Antibody [NBP1-76300] - Immunocytochemistry of KPNA4 in HeLa cells with KPNA4 antibody at 2.5 ug/mL.

Applications for Importin alpha 3/KPNA4 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

2.5-20 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin alpha 3/KPNA4

Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-alpha-induced nuclear import of NF-kappaB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.

Long Name

Karyopherin alpha 4

Alternate Names

KPNA4, QIP12, SRP3

Gene Symbol

KPNA4

UniProt

EAW78632 (Human)

Additional Importin alpha 3/KPNA4 Products

Product Documents for Importin alpha 3/KPNA4 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Importin alpha 3/KPNA4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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