Importin alpha 5/KPNA1/SRP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-54603

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Importin alpha 5/KPNA1 Antibodies »

Product Summary for Importin alpha 5/KPNA1/SRP1 Antibody

Immunogen

Synthetic peptides corresponding to KPNA1(karyopherin alpha 1 (importin alpha 5)) The peptide sequence was selected from the N terminal of KPNA1. Peptide sequence TTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVA. The peptide sequence for this immunogen was taken from within the described region.

Specificity

This product is specific to Subunit or Isoform: alpha-1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Importin alpha 5/KPNA1/SRP1 Antibody

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603] - Human Fetal Heart, Antibody Dilution: 1.0 ug/ml.
Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603]

Western Blot: Importin alpha 5/KPNA1/SRP1 Antibody [NBP1-54603] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

Applications for Importin alpha 5/KPNA1/SRP1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Importin alpha 5/KPNA1

Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNA1 interacts with RAG1 and may play a role in V(D)J recombination.Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The protein encoded by this gene interacts with RAG1 and may play a role in V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Alternate Names

IPOA5, KPNA1, NPI-1, RCH2, SRP1

Gene Symbol

KPNA1

UniProt

P52294 (Human)

Additional Importin alpha 5/KPNA1 Products

Product Documents for Importin alpha 5/KPNA1/SRP1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Importin alpha 5/KPNA1/SRP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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