INF2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81836

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all INF2 Antibodies »

Product Specifications

Immunogen

INF2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human INF2. Amino Acid Squence: KEKLGPQDSDPTEANLES

Specificity

INF2 Antibody is predicted to not cross-react with other INF1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for INF2 Antibody - BSA Free

Western Blot: INF2 AntibodyBSA Free [NBP2-81836]

Western Blot: INF2 AntibodyBSA Free [NBP2-81836]

Western Blot: INF2 Antibody [NBP2-81836] - Western blot analysis of INF2 in (A) human tonsil and (B) rat stomach tissue lysate with INF2 antibody at 1 ug/mL.

Applications for INF2 Antibody - BSA Free

Application
Recommended Usage

Western Blot

1-2 ug/mL

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INF2

Actin filaments grow only when actin monomers have access to the fast-growing barbed end of the filament. The geometry of the filament network depends on the actions of the ARP2/3 complex (MIM 604221) and members of the formin family, such as INF2. The ARP2/3 complex binds to the sides of preexisting filaments and nucleates filaments whose barbed ends are quickly blocked by capping proteins, producing brush-like structures, such as those found at the leading edges of crawling cells. In contrast, formins bind to the barbed ends of growing filaments and protect them from capping, creating long filaments that can be cross-linked into bundles, such as those found in actin cables of yeast. Interaction of formins with actin barbed ends occurs through the formin homology-2 (FH2) domain. FH2 domains accelerate filament nucleation, move with the barbed end as the filament grows, and block capping of the barbed end by proteins such as gelsolin (GSN; MIM 137350). The FH1 domain of formins binds to profilin (see MIM 176610) and accelerates elongation from the FH2-bound barbed ends (Bindschadler and McGrath, 2004 [PubMed 15466701]; Chhabra and Higgs, 2006 [PubMed 16818491]).[supplied by OMIM]

Alternate Names

C14orf151, C14orf173DKFZp762A0214, chromosome 14 open reading frame 151, chromosome 14 open reading frame 173, FLJ22056, FSGS5, HBEAG-binding protein 2 binding protein C, HBEBP2-binding protein C, inverted formin, FH2 and WH2 domain containing, inverted formin-2, MGC13251, pp9484

Gene Symbol

INF2

Additional INF2 Products

Product Documents for INF2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for INF2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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