Inhibin alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-26096

Novus Biologicals, part of Bio-Techne
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NBP2-26096
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Key Product Details

Species Reactivity

Human, Bovine

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Inhibin A Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RPLHVRTTSDGGYS corresponding to C-Terminus according to NP_002182.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Inhibin alpha Antibody

Immunohistochemistry-Paraffin: Inhibin alpha Antibody [NBP2-26096]

Immunohistochemistry-Paraffin: Inhibin alpha Antibody [NBP2-26096]

Immunohistochemistry-Paraffin: Inhibin alpha Antibody [NBP2-26096] - 60X image of Hu Testis stained with Inhibin alpha antibody at 1:50 shows questionable punctate or vesicular staining, both cytoplasmic and somewhat nuclear, in fluorescent green 488. Did not correspond completely with multiple other INHA antibodies tested. IHC staining with citrate pH 6 antigen retrieval; detected staining with a 488-conjugated anti-goat secondary antibody. IHC image submitted by a verified customer review.

Applications for Inhibin alpha Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:128000

Western Blot

1:100 - 1:2000
Application Notes
This Inhibin alpha antibody is validated for IHC-P from a verified customer review.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 3 using NBP2-26096 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Inhibin A

INHA(A-inhibin subunit precursor, inhibin alpha subunit ),also called inhibin(alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.

Alternate Names

INHA, Inhibin A

Entrez Gene IDs

3623 (Human)

Gene Symbol

INHA

Additional Inhibin A Products

Product Documents for Inhibin alpha Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Inhibin alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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