Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all INSM1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1. The immunogen is located within amino acids 90 - 140 of IA-1. Amino Acid Squence: YSPTRPVSREHEKHKYFER

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for INSM1 Antibody - BSA Free

Western Blot: INSM1 AntibodyBSA Free [NBP1-76307]

Western Blot: INSM1 AntibodyBSA Free [NBP1-76307]

Western Blot: INSM1 Antibody [NBP1-76307] - analysis of INSM1 in LnCaP cells using anti-INSM1 antibody. Image from verified customer review.
Western Blot: INSM1 AntibodyBSA Free [NBP1-76307]

Western Blot: INSM1 AntibodyBSA Free [NBP1-76307]

Western Blot: INSM1 Antibody [NBP1-76307] - Rat thymus tissue lysate with INSM1 antibody at 1 ug/mL.

Applications for INSM1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Reviewed Applications

Read 1 review rated 4 using NBP1-76307 in the following applications:

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: INSM1

IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.

Alternate Names

IA1IA-1, insulinoma-associated 1, insulinoma-associated protein 1, Zinc finger protein IA-1

Gene Symbol

INSM1

UniProt

NP_002187 (Human)

Additional INSM1 Products

Product Documents for INSM1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for INSM1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.