Insulin Antibody (E2-E3 + 2D11-H5 (same as INS04 + INS05)) [Janelia Fluor® 549]

Janelia Fluor 549

Monoclonal Mouse IgG1 Kappa/IgG1 Kappa Clone # E2-E3 + 2D11-H5 (same as INS04 + INS05)

Please see the vial label for concentration. If unlisted please contact technical services.

Purified pig insulin, conjugated to KLH (E2-E3 & 2D11-H5) (Uniprot: P01308)

Cytoplasmic

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

beta-Cell & Insulinoma Marker

Monoclonal

Mouse

IgG1 Kappa/IgG1 Kappa

Protein G purified

50mM Sodium Borate

0.05% Sodium Azide

Please see the vial label for concentration. If unlisted please contact technical services.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C in the dark.