Insulin Receptor beta Antibody (C18C4)

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-19192

Novus Biologicals, part of Bio-Techne
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NBP1-19192-0.05mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Porcine, Bovine, Hamster, Rabbit, Sheep

Cited:

Rat

Applications

Validated:

Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # C18C4

Concentration

1.0 mg/ml

View all Insulin Receptor beta Antibodies »

Product Specifications

Immunogen

Recombinant cytoplasmic domain of human Insulin Receptor beta

Specificity

Insulin Receptor beta (C18C4)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Insulin Receptor beta Antibody (C18C4)

Western Blot: Insulin Receptor beta Antibody (C18C4) [NBP1-19192]

Western Blot: Insulin Receptor beta Antibody (C18C4) [NBP1-19192]

Western Blot: Insulin Receptor beta Antibody (C18C4) [NBP1-19192] - Lane 1: MW Marker, Lane 2: HeLa lysate, Lane 3: MCF-7 lysate, Lane 4: PC-12 lysate, Lane 5: 3T3 lysate.

Applications for Insulin Receptor beta Antibody (C18C4)

Application
Recommended Usage

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.2) and 50% Glycerol

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Insulin Receptor beta

The Insulin Receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. InsR is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional autophosphorylation sites such as tyrosine residues 960, 972, 1316, and 1322 regulate the assembly of signal transduction complexes.

Alternate Names

CD220, CD220 antigen, EC 2.7.10, EC 2.7.10.1, HHF5, insulin receptor, IR

Entrez Gene IDs

3643 (Human); 16337 (Mouse); 24954 (Rat)

Gene Symbol

INSR

Additional Insulin Receptor beta Products

Product Documents for Insulin Receptor beta Antibody (C18C4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Insulin Receptor beta Antibody (C18C4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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