Integrin alpha 1/CD49a Antibody (CL7207)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76478

Novus Biologicals, part of Bio-Techne
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NBP2-76478
NBP2-76478-25ul
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Key Product Details

Validated by

Knockout/Knockdown, Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Block/Neutralize, Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Cited:

Block/Neutralize

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7207

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 1/CD49a Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RQISRSFFSGTQERKVQRN

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 1/CD49a Antibody (CL7207)

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Analysis in human prostate and skeletal muscle tissues. Corresponding ITGA1 RNA-seq data are presented for the same tissues.
Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Western Blot: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Analysis in U-138MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ITGA1 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478]

Immunohistochemistry-Paraffin: Integrin alpha 1/CD49a Antibody (CL7207) [NBP2-76478] - Staining of human placenta shows strong membranous positivity in blood vessels and loose connective tissue of chorionic villi.
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Applications for Integrin alpha 1/CD49a Antibody (CL7207)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Use in Block/Neutralize reported in scientific literature (PMID:31750298).

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 1/CD49a

Integrin alpha 1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq]

Alternate Names

CD49a, ITGA1, VLA-1

Gene Symbol

ITGA1

Additional Integrin alpha 1/CD49a Products

Product Documents for Integrin alpha 1/CD49a Antibody (CL7207)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 1/CD49a Antibody (CL7207)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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