Integrin alpha 2/CD49b Antibody (AK7) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09132

Clone AK7 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP3-09132
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Key Product Details

Species Reactivity

Human, Primate

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # AK7

Format

BSA Free

Concentration

1 mg/ml

View all Integrin alpha 2/CD49b Antibodies »

Product Specifications

Immunogen

Human platelets

Specificity

The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 2/CD49b Antibody (AK7) - BSA Free

Flow Cytometry: Integrin alpha 2/CD49b Antibody (AK7) - BSA Free [NBP3-09132]

Flow Cytometry: Integrin alpha 2/CD49b Antibody (AK7) - BSA Free [NBP3-09132]

Flow Cytometry: Integrin alpha 2/CD49b Antibody (AK7) [NBP3-09132] - Analysis (surface staining) of CD49b in human peripheral blood with anti-CD49b (AK7) purified / GAM-APC

Applications for Integrin alpha 2/CD49b Antibody (AK7) - BSA Free

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunohistochemistry-Frozen

5-10 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (AK7) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (AK7) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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