Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-44393

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL7318

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all Integrin alpha 2/CD49b Antibodies »

Product Specifications

Immunogen

This antibody was generated using a recombinant protein sequence of P17301, with the exact immunogen sequence remaining proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Analysis in human skin and skeletal muscle tissues using NBP3-44393 antibody. Corresponding Integrin alpha 2/CD49b RNA-seq data are presented for the same tissues.
Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human skeletal muscle shows no positivity in striated muscle fibers as expected.
Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Immunohistochemistry-Paraffin: Integrin alpha 2/CD49b Antibody [NBP3-44393]

Staining of human prostate shows moderate membranous positivity in glandular cells.
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Applications for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Reconstitution

Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS with Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (CL7318) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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