Integrin alpha 3/CD49c Antibody (ASC-1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62200

Clone ASC-1 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # ASC-1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 3/CD49c Antibodies »

Product Specifications

Immunogen

Human SSC-9 cell line (squamous cell carcinoma)

Specificity

The antibody HTF-14 recognizes an epitope located in the N-terminal domain of human serum transferrin, a 77 kDa single polypeptide chain glycoprotein (member of the iron binding family of proteins). It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Theoretical MW

125 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin alpha 3/CD49c Antibody (ASC-1)

Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200]

Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200]

Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200] - Surface staining of HeLa cells with anti-CD49c (ASC-1) PE.
Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200]

Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200]

Flow (Cell Surface): Integrin alpha 3/CD49c Antibody (ASC-1) [NBP2-62200] - Surface staining of HeLa cells with anti-CD49c (ASC-1) purified, GAM-APC.

Applications for Integrin alpha 3/CD49c Antibody (ASC-1)

Application
Recommended Usage

Flow Cytometry

1-4 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Integrin alpha 3/CD49c

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3).

Alternate Names

CD49c, ITGA3

Gene Symbol

ITGA3

Additional Integrin alpha 3/CD49c Products

Product Documents for Integrin alpha 3/CD49c Antibody (ASC-1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Integrin alpha 3/CD49c Antibody (ASC-1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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