Integrin alpha 3/CD49c Antibody (CL6937)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76515

Novus Biologicals, part of Bio-Techne
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NBP2-76515
NBP2-76515-25ul
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Key Product Details

Validated by

Knockout/Knockdown, Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL6937

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 3/CD49c Antibodies »

Product Summary for Integrin alpha 3/CD49c Antibody (CL6937)

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: AQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPPGACQANETIFCELGNPFKRNQRMELLIAFEVIGV

Epitope

KCESNLQMRAAFVSE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84)% and Rat (82)%

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha 3/CD49c Antibody (CL6937)

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ITGA3 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Immunohistochemistry-Paraffin: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Staining of human liver shows no positivity in hepatocytes as expected.
Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515]

Western Blot: Integrin alpha 3/CD49c Antibody (CL6937) [NBP2-76515] - Analysis in human cell line U-87 MG.
View 4 more images

Applications for Integrin alpha 3/CD49c Antibody (CL6937)

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:250

Immunohistochemistry-Paraffin

1:100 - 1:250

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 3/CD49c

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3).

Alternate Names

CD49c, ITGA3

Gene Symbol

ITGA3

Additional Integrin alpha 3/CD49c Products

Product Documents for Integrin alpha 3/CD49c Antibody (CL6937)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 3/CD49c Antibody (CL6937)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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