Integrin alpha 3/CD49c Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75266

Novus Biologicals, part of Bio-Techne
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NB100-75266
NB100-75266-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha 3/CD49c Antibodies »

Product Summary for Integrin alpha 3/CD49c Antibody

Immunogen

The immunogen for this antibody was a sequence from 1015a.a. to 1051a.a. from Integrin alpha-3(a 1051a.a. long protein)

Reactivity Notes

This antibody is reactive against Human, rat.

Localization

Membrane; single-pass type I membrane protein.

Specificity

Integrin alpha 3

Clonality

Polyclonal

Host

Chicken

Scientific Data Images for Integrin alpha 3/CD49c Antibody

Western Blot: Integrin alpha 3/CD49c Antibody [NB100-75266]

Western Blot: Integrin alpha 3/CD49c Antibody [NB100-75266]

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-ITGA3)

Applications for Integrin alpha 3/CD49c Antibody

Application
Recommended Usage

Western Blot

1:200 - 1:500
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2)

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 3/CD49c

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA3), very common antigen 2 (VCA2), extracellular matrix receptor 1 (ECMR1), and galactoprotein b3 (GAPB3). Integrin alpha-3/beta-1 is a receptor for fibronectin. laminin. collagen. epiligrin. thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Alternate Names

CD49c, ITGA3

Entrez Gene IDs

3675 (Human); 360606 (Rat)

Gene Symbol

ITGA3

UniProt

P26006 (Human)

Additional Integrin alpha 3/CD49c Products

Product Documents for Integrin alpha 3/CD49c Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha 3/CD49c Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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