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Integrin alpha D/CD11d Antibody (CA11.8H2)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-65292

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Canine

Cited:

Canine

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Cited:

Flow Cytometry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CA11.8H2

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Affinity purified CD11 antigen from canine spleen

Specificity

NB100-65292 recognizes the canine CD11d cell surface antigen (the integrin ad sub-unit). The ad integrin is a newly recognized integrin chain that is expressed as a heterodimer with the b2 integrin (CD18). CD11d is expressed by a sub-population of CD8 positive T cells, macrophages and by gd T cells in the splenic red pulp.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Integrin alpha D/CD11d Antibody (CA11.8H2)

Flow Cytometry: Integrin alpha D/CD11d Antibody (CA11.8H2) - BSA Free [NB100-65292]

Flow Cytometry: Integrin alpha D/CD11d Antibody (CA11.8H2) - BSA Free [NB100-65292]

Flow Cytometry: Integrin alpha D/CD11d Antibody (CA11.8H2) [NB100-65292] - Staining of canine peripheral blood lymphocytes with Mouse anti Dog CD11d:Alexa Fluor® 647

Applications for Integrin alpha D/CD11d Antibody (CA11.8H2)

Application
Recommended Usage

Flow Cytometry

1:10-1:20

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunoprecipitation

1:10-1:500
Application Notes
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha D/CD11d

Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. May play a role in the atherosclerotic process such as clearing lipoproteins from plaques and in phagocytosis of blood-borne pathogens, particulate matter, and senescent erythrocytes from the blood

Alternate Names

ADB2, CD11d, Leukointegrin Alpha D

Gene Symbol

ITGAD

Additional Integrin alpha D/CD11d Products

Product Documents for Integrin alpha D/CD11d Antibody (CA11.8H2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin alpha D/CD11d Antibody (CA11.8H2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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