Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-97568

Clone Ber-ACT8 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne
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NBP1-97568
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NBP1-97564
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Key Product Details

Species Reactivity

Human, Primate

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # Ber-ACT8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Integrin alpha E/CD103 Antibodies »

Product Specifications

Immunogen

HTLV-1 induced human T cell line MAPS16

Specificity

The mouse monoclonal antibody Ber-ACT8 recognizes an extracellular epitope of CD103 (alpha E integrin), a type I transmembrane glycoprotein primarily found on intestinal intraepithelial lymphocytes. HLDA V; WS Code A067

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Flow Cytometry: Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC] [NBP1-97568] - Surface staining of CD103 on PHA-activated PBMC with anti-CD103 (Ber-ACT8) FITC.

Applications for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Application
Recommended Usage

Flow Cytometry

4ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunoprecipitation

1:10-1:500

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Size Exclusion Chromatography

Formulation

PBS and 0.2% (w/v) high grade BSA (protease free)

Preservative

0.9% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin alpha E/CD103

CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes, epithelial dendritic cells, lamina propria-derived dendritic cells, a subpopulation of lamina propria T cells, a small subset of peripheral lymphocytes, namely T reg cells, and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen), which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium, and, in addition to the role in adhesion, may serve as an accessory molecule for intraepithelial lymphocyte activat

Alternate Names

CD103, HUMINAE, ITGAE

Gene Symbol

ITGAE

Additional Integrin alpha E/CD103 Products

Product Documents for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Integrin alpha E/CD103 Antibody (Ber-ACT8) [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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