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Integrin beta 3/CD61 Antibody (BV4)

Novus Biologicals, part of Bio-Techne | Catalog # NB600-1342

Novus Biologicals, part of Bio-Techne
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NB600-1342

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine

Cited:

Mouse, Rat

Applications

Validated:

Functional, Immunoassay, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # BV4

Concentration

0.1 mg/ml

Product Specifications

Immunogen

Mouse Integrin alpha V beta 3

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 23857293). Mouse reactivity reported in scientific literature (PMID: 28050799).

Specificity

The monoclonal antibody BV4 recognizes human beta3 integrin subunit present in Platelet glycoprotein GPIIb-IIIa (integrin alphaIIb/beta3, CD41/CD61) and in the vitronectin receptor (integrin alphaV/beta3, CD51/CD61).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Integrin beta 3/CD61 Antibody (BV4)

Application
Recommended Usage

Immunohistochemistry

1:50

Immunohistochemistry-Frozen

1:50

Immunohistochemistry-Paraffin

1:50

Immunoprecipitation

1:10-1:500

Western Blot

1:50
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.1% BSA

Preservative

0.02% Sodium Azide

Concentration

0.1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Integrin beta 3/CD61

Human Integrin beta 3 (CD61) antigen is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex. The beta 3 integrin chain is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells.

Alternate Names

CD61, GP3A, GPIIIA, INGRB3, ITGB3

Entrez Gene IDs

3690 (Human)

Gene Symbol

ITGB3

UniProt

Additional Integrin beta 3/CD61 Products

Product Documents for Integrin beta 3/CD61 Antibody (BV4)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Integrin beta 3/CD61 Antibody (BV4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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