Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37392

Novus Biologicals, part of Bio-Techne
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NBP2-37392
NBP2-37392-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 10B10D5

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all Integrin beta 4/CD104 Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human Integrin beta 4/CD104 (AA: 1619-1822) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

202 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free

Western Blot: Integrin beta 4/CD104 Antibody (10B10D5)BSA Free [NBP2-37392]

Western Blot: Integrin beta 4/CD104 Antibody (10B10D5)BSA Free [NBP2-37392]

Western Blot: Integrin beta 4/CD104 Antibody (10B10D5) [NBP2-37392] - Analysis using ITGB4 mouse mAb against A549 (1), A431 (2), MCF-7 (3) and SW620 (4) cell lysate.
Immunohistochemistry-Paraffin: Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free [NBP2-37392]

Immunohistochemistry-Paraffin: Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free [NBP2-37392]

Immunohistochemistry-Paraffin: Integrin beta 4/CD104 Antibody (10B10D5) [NBP2-37392] - Analysis of esophageal cancer tissues using ITGB4 mouse mAb with DAB staining.
Flow Cytometry: Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free [NBP2-37392]

Flow Cytometry: Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free [NBP2-37392]

Flow Cytometry: Integrin beta 4/CD104 Antibody (10B10D5) [NBP2-37392] - Analysis of A549 cells using ITGB4 mouse mAb (green) and negative control (purple).
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Applications for Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200 - 1:400

Immunohistochemistry

1:200 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:1000

Western Blot

1:500 - 1:2000

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin beta 4/CD104

Integrin beta 4 is a glycoprotein which associates with the a6 integrin to form the a6/b4 complex. Integrin alpha 6/beta 4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Defects in Integrin beta 4 gene are a cause of epidermolysis bullosa letalis with pyloric atresia (EB PA); also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is characterized by mucocutaneous fragility and gastrointestinal atresia, which most commonly affects the pylorus. Moreover, defects in Integrin beta 4 gene are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). This nonlethal form of junctional epidermolysis bullosa is characterized by life long blistering of the skin, associated with hair and tooth abnormalities.

Alternate Names

CD104, ITGB4

Gene Symbol

ITGB4

Additional Integrin beta 4/CD104 Products

Product Documents for Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Integrin beta 4/CD104 Antibody (10B10D5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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