Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: Integrin beta 4/CD104

Integrin beta 4 is a glycoprotein which associates with the a6 integrin to form the a6/b4 complex. Integrin alpha 6/beta 4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Defects in Integrin beta 4 gene are a cause of epidermolysis bullosa letalis with pyloric atresia (EB PA); also known as junctional epidermolysis bullosa with pyloric atresia (PA-JEB) or aplasia cutis congenita with gastrointestinal atresia. EB-PA is characterized by mucocutaneous fragility and gastrointestinal atresia, which most commonly affects the pylorus. Moreover, defects in Integrin beta 4 gene are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). This nonlethal form of junctional epidermolysis bullosa is characterized by life long blistering of the skin, associated with hair and tooth abnormalities.

Alternate Names

CD104, ITGB4

Gene Symbol

ITGB4

Additional Integrin beta 4/CD104 Products

Product Documents for Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43369APCCY7

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

View all Integrin beta 4/CD104 Antibodies »

Product Specifications

Immunogen

Clonality

Host

Isotype

Applications for Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

Flow Cytometry

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Integrin beta 4/CD104

Alternate Names

Gene Symbol

Additional Integrin beta 4/CD104 Products

Product Documents for Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Integrin beta 4/CD104 Antibody (439-9B) [Allophycocyanin/Cy7]

CONTACT INFORMATION

保持关注