Intra Acrosomal Protein Antibody (SR1162)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22038

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22038-100ul
NBP3-22038-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1162

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Intra Acrosomal Protein Antibodies »

Product Summary for Intra Acrosomal Protein Antibody (SR1162)

Immunogen

A synthesized peptide derived from human Intra Acrosomal Protein (Uniprot #: P26436)

Specificity

Detects endogenous levels of total Intra Acrosomal Protein

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Intra Acrosomal Protein Antibody (SR1162)

Western Blot: Intra Acrosomal Protein Antibody (SR1162) [NBP3-22038] -

Western Blot: Intra Acrosomal Protein Antibody (SR1162) [NBP3-22038] - Western blot analysis using NBP3-22038 in Human testis lysate.

Applications for Intra Acrosomal Protein Antibody (SR1162)

Application
Recommended Usage

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Intra Acrosomal Protein

Intra Acrosomal Protein is a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. The gene encoding this protein consists of 4 exons and its alternative splicing generates 11 distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining 7 transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.

Alternate Names

acrosomal protein SP-10, acrosomal vesicle protein 1D11S4365, SP-10, SPACA2, sperm protein 10

Gene Symbol

ACRV1

Additional Intra Acrosomal Protein Products

Product Documents for Intra Acrosomal Protein Antibody (SR1162)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Intra Acrosomal Protein Antibody (SR1162)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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