IP3R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-09066

Novus Biologicals, part of Bio-Techne
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NBP3-09066
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all IP3R1 Antibodies »

Product Summary for IP3R1 Antibody

Immunogen

Synthetic peptide within C-terminal human IP3R1. (SwissProt: Q14643 Human; SwissProt: P11881 Mouse; SwissProt: P29994 Rat)

Localization

Cytoplasm. Cytoplasmic vesicle. Endoplasmic reticulum. Membrane.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

314 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IP3R1 Antibody

Western Blot: IP3R1 Antibody [NBP3-09066]

Western Blot: IP3R1 Antibody [NBP3-09066]

Western Blot: IP3R1 Antibody [NBP3-09066] - Western blot analysis of IP3 Receptor on Hela cell lysate using anti-IP3 Receptor antibody at 1/500 dilution.
Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP3-09066]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP3-09066]

Immunohistochemistry-Paraffin: IP3R1 Antibody [NBP3-09066] - Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IP3 Receptor antibody. Counter stained with hematoxylin.
Flow Cytometry: IP3R1 Antibody [NBP3-09066]

Flow Cytometry: IP3R1 Antibody [NBP3-09066]

Flow Cytometry: IP3R1 Antibody [NBP3-09066] - Flow cytometric analysis of SH-SY-5Y cells with IP3 Receptor antibody at 1/100 dilution (fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
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Applications for IP3R1 Antibody

Application
Recommended Usage

Flow Cytometry

1:50-1:100

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH7.4), 0.2% BSA, 50% Glycerol

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IP3R1

IP3R1 (inositol 1,4,5-triphosphate receptor type 1) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian InsP3R receptors: Insp3R1, Insp3R2, and Insp3R3. Defects in the gene which encodes InsP3R1, ITPR1, are the cause of spinocerebellar ataxia type 15 (SCA15).

Long Name

Inositol 1,4,5-trisphosphate receptor type 1

Alternate Names

InsP3R1, IP3R 1, ITPR1

Gene Symbol

ITPR1

Additional IP3R1 Products

Product Documents for IP3R1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IP3R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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