Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all IP3R3 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 625 and 675 of human inositol 1,4,5-triphosphate receptor, type 3 using the numbering given in entry NP_002215.2 (GeneID 3710).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IP3R3 Antibody

Immunohistochemistry-Paraffin: IP3R3 Antibody [NBP1-21399]

Immunohistochemistry-Paraffin: IP3R3 Antibody [NBP1-21399]

Immunohistochemistry-Paraffin: IP3R3 Antibody [NBP1-21399] - Section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-IP3R3 used at a dilution of 1:1,000 (1ug/ml). Detection: DAB
Immunoprecipitation: IP3R3 Antibody [NBP1-21399]

Immunoprecipitation: IP3R3 Antibody [NBP1-21399]

Immunoprecipitation: IP3R3 Antibody [NBP1-21399] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Affinity purified rabbit anti-IP3R3 antibody used for IP at 3 mcg/mg lysate. IP3R3 was also immunoprecipitated by rabbit anti-IP3R3 antibody NBP1-21400 which recognizes a downstream e

Applications for IP3R3 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:500 - 1:2000

Immunoprecipitation

2 - 10 ug/mg lysate
Application Notes
Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: IP3R3

IP3R3 (inositol 1,4,5-triphosphate receptor type 3) is an intracellular calcium release channel that mediates calcium release from the endoplasmic reticulum. There are 3 mammalian IP3R receptors: IP3R1, IP3R2, and IP3R3. IP3R3 has been shown to play a role in olfactory mucus secretion and in the taste perception of sweet, savory (umami), and bitter substances.

Long Name

Inositol 1,4,5-trisphosphate receptor type 3

Alternate Names

InsP3R3, IP3R 3, ITPR3

Entrez Gene IDs

3710 (Human)

Gene Symbol

ITPR3

UniProt

NP_002215.2 (Human)

Additional IP3R3 Products

Product Documents for IP3R3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IP3R3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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