IRF1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24921

Novus Biologicals, part of Bio-Techne
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NBP3-24921
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IRF1 Antibodies »

Product Summary for IRF1 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein IRF1 using the following amino acid sequence: PALSPCAVSSTLPDWHIPVEVVPDSTSDLYNFQVSPMPSTSEATTDEDEEGKLPEDIMKLLE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IRF1 Antibody

IRF1 Antibody Immunocytochemistry/Immunofluorescence: IRF1 Antibody [NBP3-24921]

Immunocytochemistry/Immunofluorescence: IRF1 Antibody [NBP3-24921]

Staining of human cell line HaCaT shows localization to nucleoplasm.

Applications for IRF1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IRF1

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

Long Name

Interferon Regulatory Factor 1

Alternate Names

MAR

Gene Symbol

IRF1

Additional IRF1 Products

Product Documents for IRF1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for IRF1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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