IRS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-16992

Novus Biologicals, part of Bio-Techne
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NBP2-16992
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all IRS1 Antibodies »

Product Summary for IRS1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human IRS1. The exact sequence is proprietary.

Reactivity Notes

Pig (85%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

132 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for IRS1 Antibody

Western Blot: IRS1 Antibody [NBP2-16992]

Western Blot: IRS1 Antibody [NBP2-16992]

Western Blot: IRS1 Antibody [NBP2-16992] - Various whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with IRS1 antibody [C2C3], C-term diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody
Immunohistochemistry-Paraffin: IRS1 Antibody [NBP2-16992]

Immunohistochemistry-Paraffin: IRS1 Antibody [NBP2-16992]

Immunohistochemistry-Paraffin: IRS1 Antibody [NBP2-16992] - Paraffin-embedded lung carcinoma. IRS1 antibody [C2C3], C-term dilution: 1:500.
Western Blot: IRS1 Antibody [NBP2-16992]

Western Blot: IRS1 Antibody [NBP2-16992]

Western Blot: IRS1 Antibody [NBP2-16992] - Sample (30 ug of whole cell lysate) A: A431 5% SDS PAGE gel, diluted at 1:10000.

Applications for IRS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: IRS1

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq]

Long Name

Insulin Receptor Substrate 1

Alternate Names

HIRS-1, insulin receptor substrate 1, IRS-1

Gene Symbol

IRS1

UniProt

P35568

Additional IRS1 Products

Product Documents for IRS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for IRS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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