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ITM2B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88354

Novus Biologicals, part of Bio-Techne
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NBP1-88354
NBP1-88354-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (95%), Rat (96%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YFALQPDDVYYCGIKYIKDDVILNEPSADAPAALYQTIEENIKIFEEEEVEFISVPVPEFADSDPANIVHDFNKKLTAYLDLNLDKCYVIPLNTSIVMPPRNLLELLINIKAGTYLPQSYLIHEHMVITDRIENIDHLGFFIYRLCH

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25557390).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ITM2B Antibody

Immunocytochemistry/ Immunofluorescence: ITM2B Antibody [NBP1-88354]

Immunocytochemistry/ Immunofluorescence: ITM2B Antibody [NBP1-88354]

Immunocytochemistry/Immunofluorescence: ITM2B Antibody [NBP1-88354] - Staining of human cell line U-251 MG shows localization to the Golgi apparatus & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354]

Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354]

Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354] - Staining of human cerebral cortex shows strong granular cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354]

Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354]

Immunohistochemistry-Paraffin: ITM2B Antibody [NBP1-88354] - Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Applications for ITM2B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100. IHC and WB reported in scientific literature (PMID: 25557390)

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITM2B

ITM2B is a type II membrane protein. It is expressed in brain and in other tissues. Defects in ITM2B seem to be associated with familial British dementia (FBD) and familial Danish dementia (FDD).

Long Name

Integral Membrane Protein 2B

Alternate Names

ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD

Gene Symbol

ITM2B

Additional ITM2B Products

Product Documents for ITM2B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ITM2B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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