ITPKA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81590

Novus Biologicals, part of Bio-Techne
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NBP1-81590
NBP1-81590-25ul
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ITPKA Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DGSCSTDFKTTRSREQVLRVFEEFVQGDEEVLRRYLNRLQQIRDTLEVSEFFRRHEV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for ITPKA Antibody

Immunocytochemistry/ Immunofluorescence: ITPKA Antibody [NBP1-81590]

Immunocytochemistry/ Immunofluorescence: ITPKA Antibody [NBP1-81590]

Immunocytochemistry/Immunofluorescence: ITPKA Antibody [NBP1-81590] - Staining of human cell line U-251 MG shows localization to vesicles. Antibody staining is shown in green.
ITPKA Antibody Western Blot: ITPKA Antibody [NBP1-81590]

Western Blot: ITPKA Antibody [NBP1-81590]

analysis in human cerebral cortex tissue.

Applications for ITPKA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ITPKA

Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region. (provided by RefSeq)

Alternate Names

EC 2.7.1.127, inositol 14,5-trisphosphate 3-kinase AIP3 3-kinase A, inositol-trisphosphate 3-kinase A, InsP 3-kinase A, IP3-3KA, IP3K A, IP3KA

Gene Symbol

ITPKA

Additional ITPKA Products

Product Documents for ITPKA Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ITPKA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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