JAM-A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38934

Novus Biologicals, part of Bio-Techne
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NBP2-38934
NBP2-38934-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all JAM-A Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VHSSEPEVRIPENNPVKLSCAYSGFSSPRVEWKFDQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JAM-A Antibody

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934] - Staining of human placenta shows high expression.
Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934] - Staining of human oral mucosa shows moderate cell membranous positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934]

Immunohistochemistry-Paraffin: JAM-A Antibody [NBP2-38934] - Staining of human pancreas shows low expression as expected.
View 1 more images

Applications for JAM-A Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: JAM-A

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Long Name

Junctional Adhesion Molecule A

Alternate Names

CD321, F11R, JAMA, PAM-1

Gene Symbol

F11R

UniProt

Q9Y624

Additional JAM-A Products

Product Documents for JAM-A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for JAM-A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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