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JNK1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1925

Novus Biologicals, part of Bio-Techne
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NB100-1925
NB100-1925SS

Key Product Details

Species Reactivity

Validated:

C. elegans, Human (Negative), Mammal (Negative), Mouse (Negative), Rat (Negative)

Cited:

Nematode - Caenorhabditis elegans

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Product Specifications

Immunogen

A recombinant protein made to the C-terminus (residues 228-451) of the C. elegans JNK1 alpha protein.

Reactivity Notes

This antibody does not appear to detect mammalian JNK protein.

Localization

Neuronal

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for JNK1 Antibody

Western Blot: JNK1 Antibody [NB100-1925]

Western Blot: JNK1 Antibody [NB100-1925]

Western Blot: JNK1 Antibody [NB100-1925] - Detection of JNK-1 using NB100-1925.

Applications for JNK1 Antibody

Application
Recommended Usage

ELISA

1:100-1:2000

Immunohistochemistry

1:200-1:500

Immunohistochemistry-Paraffin

1:200-1:500

Western Blot

1:2000
Application Notes
This JNK1 antibody is useful for ELISA, Immunohistochemistry-Paraffin and Western blot where a band can be seen at ~53kDa (alpha form) and at ~42kDa (beta form).

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Whole antisera

Preservative

0.05% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: JNK1

The insulin signaling pathway plays a pivotal role in lifespan regulation and stress resistance in many diverse organisms. Components of the JNK (c-Jun N-terminal kinase) signaling pathway have been shown to interact with the insulin signaling pathway. The JNK family is a subgroup of the mitogen-activated protein kinase superfamily and is part of a signal transduction cascade that is activated by cytokines and by exposure to environmental stresses. Thus, JNK1 plays a role in regulating both life span and stress resistance.

Long Name

C-Jun N-terminal Kinase 1

Alternate Names

MAPK8, PRKM8, SAPK1

Entrez Gene IDs

5599 (Human); 177460 (C. elegans)

Gene Symbol

MAPK8

Additional JNK1 Products

Product Documents for JNK1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for JNK1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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