KAT2A/GCN5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17017

Novus Biologicals, part of Bio-Techne
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NBP2-17017
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Chicken (96%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KAT2A/GCN5 Antibodies »

Product Summary for KAT2A/GCN5 Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human KAT2A/GCN5. The exact sequence is proprietary.

Localization

Nucleus

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

94 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KAT2A/GCN5 Antibody

Western Blot: KAT2A/GCN5 Antibody [NBP2-17017]

Western Blot: KAT2A/GCN5 Antibody [NBP2-17017]

Western Blot: KAT2A/GCN5 Antibody [NBP2-17017] - Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with GCN5 antibody [C2C3], C-term diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: KAT2A/GCN5 Antibody [NBP2-17017]

Immunocytochemistry/ Immunofluorescence: KAT2A/GCN5 Antibody [NBP2-17017]

Immunocytochemistry/Immunofluorescence: KAT2A/GCN5 Antibody [NBP2-17017] - Analysis of paraformaldehyde-fixed MCF-7, using antibody at 1:500 dilution.
Western Blot: KAT2A/GCN5 Antibody [NBP2-17017]

Western Blot: KAT2A/GCN5 Antibody [NBP2-17017]

Western Blot: KAT2A/GCN5 Antibody [NBP2-17017] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC C: BCL-1 7. 5% SDS PAGE gel, diluted at 1:1000.
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Applications for KAT2A/GCN5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KAT2A/GCN5

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM]

Long Name

Lysine Acetyltransferase 2A

Alternate Names

GCN5L2, HGCN5, KAT2A, PCAF-B

Gene Symbol

KAT2A

UniProt

Q92830 (Human)

Additional KAT2A/GCN5 Products

Product Documents for KAT2A/GCN5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KAT2A/GCN5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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