KCC3/SLC12A6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89282

Novus Biologicals, part of Bio-Techne
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NBP1-89282
NBP1-89282-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (94%), Rat (93%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KCC3/SLC12A6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RVRFSSRESVPETSRSEPMSEMSGATTSLATVALDPPSDRTSHPQDVIEDLSQNSITGEHSQLLDDGHKKARNAYLNNSNYEEGDE

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 25110711).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KCC3/SLC12A6 Antibody

Immunocytochemistry/ Immunofluorescence: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunocytochemistry/ Immunofluorescence: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunocytochemistry/Immunofluorescence: KCC3/SLC12A6 Antibody [NBP1-89282] - Staining of human cell line A-431 shows localization to cytosol & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282] - Staining of human Lymph node shows moderate membranous and cytoplasmic positivity in germinal and non-germinal center cells.
Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282]

Immunohistochemistry-Paraffin: KCC3/SLC12A6 Antibody [NBP1-89282] - Staining of human cerebral cortex shows moderate to strong cytoplasmic positivity in neurons.
View 2 more images

Applications for KCC3/SLC12A6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KCC3/SLC12A6

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq]

Long Name

K-Cl Cotransporter 3

Alternate Names

ACCPN, SLC12A6

Gene Symbol

SLC12A6

Additional KCC3/SLC12A6 Products

Product Documents for KCC3/SLC12A6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KCC3/SLC12A6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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