KCNK1 Antibody (4D7)

Novus Biologicals, part of Bio-Techne | Catalog # H00003775-M01-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 4D7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KCNK1 Antibodies »

Product Specifications

Immunogen

KCNK1 (NP_002236.1, 265 a.a. ~ 336 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ETFCELHELKKFRKMFYVKKDKDEDQVHIIEHDQLSFSSITDQAAGMKEDQKQNEPFVATQSSACVDGPANH

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for KCNK1 Antibody (4D7)

Western Blot: KCNK1 Antibody (4D7) [H00003775-M01-100ug]

Western Blot: KCNK1 Antibody (4D7) [H00003775-M01-100ug]

Western Blot: KCNK1 Antibody (4D7) [H00003775-M01-100ug] - Detection against Immunogen (33.66 KDa) .
ELISA: KCNK1 Antibody (4D7) [H00003775-M01-100ug]

ELISA: KCNK1 Antibody (4D7) [H00003775-M01-100ug]

ELISA: KCNK1 Antibody (4D7) [H00003775-M01-100ug] - Detection limit for recombinant GST tagged KCNK1 is 0.1 ng/ml as a capture antibody.

Applications for KCNK1 Antibody (4D7)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KCNK1

K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34% homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.

Long Name

Potassium channel subfamily K member 1

Alternate Names

HOHO1, KCNO1, TWIK1

Entrez Gene IDs

3775 (Human)

Gene Symbol

KCNK1

OMIM

601745 (Human)

UniProt

NP_002236.1 (Human)

Additional KCNK1 Products

Product Documents for KCNK1 Antibody (4D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KCNK1 Antibody (4D7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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