KHDRBS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81148

Novus Biologicals, part of Bio-Techne
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NBP1-81148
NBP1-81148-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KHDRBS2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PDYNDEIRQEQLRELSYLNGSEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KHDRBS2 Antibody

Western Blot: KHDRBS2 Antibody [NBP1-81148]

Western Blot: KHDRBS2 Antibody [NBP1-81148]

Western Blot: KHDRBS2 Antibody [NBP1-81148] - Analysis in control (vector only transfected HEK293T lysate) and KHDRBS2 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: KHDRBS2 Antibody [NBP1-81148]

Immunohistochemistry-Paraffin: KHDRBS2 Antibody [NBP1-81148]

Immunohistochemistry-Paraffin: KHDRBS2 Antibody [NBP1-81148] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.

Applications for KHDRBS2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KHDRBS2

RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splicesite selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection.Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-richexonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U)homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability

Alternate Names

hSLM-1, KH domain containing, RNA binding, signal transduction associated 2, KH domain-containing, RNA-binding, signal transduction-associated protein 2, MGC26664, Sam68-like mammalian protein 1, SLM1bA535F17.1, SLM-1FLJ38664

Entrez Gene IDs

202559 (Human)

Gene Symbol

KHDRBS2

UniProt

Q5VWX1 (Human)

Additional KHDRBS2 Products

Product Documents for KHDRBS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KHDRBS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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