KIF14 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB110-40678

Novus Biologicals, part of Bio-Techne
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NB110-40678
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all KIF14 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1600 and the C-terminus (residue 1648) of human Kinesin Family Member 14 using the numbering given in entry NP_055690.1 (GeneID 9928).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KIF14 Antibody

Western Blot: KIF14 Antibody [NB110-40678]

Western Blot: KIF14 Antibody [NB110-40678]

Western Blot: KIF14 Antibody [NB110-40678] - Detection of Human KIF14 on HeLa whole cell lysate using NB110-40678. KIF14 was also immunoprecipitated by other rabbit anti-KIF14 antibodies.
Immunohistochemistry: KIF14 Antibody [NB110-40678]

Immunohistochemistry: KIF14 Antibody [NB110-40678]

Immunohistochemistry: KIF14 Antibody [NB110-40678] - Sample: FFPE section of human breast carcinoma (left) and formaldelyde-fixed HeLa cells (right). Antibody: Affinity purified rabbit anti-KIF14 used at a dilution of 1:200 (1ug/ml) and 1:100 (2ug/ml). Detection: DAB (left) and red-fluorescent goat anti-rab

Applications for KIF14 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KIF14

The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination and speed of the transportation of a variety of important functional molecules, including mRNA. KIFs are involved in neuronal function and development. Kinesin family member 14 (KIF14) is an overexpressed potential oncogene in the 1q region of genomic gain in breast cancer cell lines associated with poor prognosis breast cancer. The gain of chromosome 1q likely reflects oncogene amplification. As such KIF14 may be a potential therapeutic target and indicator of oncogenesis.

Alternate Names

KIAA0042MGC142302, kinesin family member 14, kinesin-like protein KIF14

Entrez Gene IDs

9928 (Human)

Gene Symbol

KIF14

UniProt

NP_055690.1 (Human)

Additional KIF14 Products

Product Documents for KIF14 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for KIF14 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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