KIF1B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-57494

Novus Biologicals, part of Bio-Techne
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NB100-57494
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all KIF1B Antibodies »

Product Summary for KIF1B Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 1766 and the C-terminus (residue 1816) of human kinesin family member 1B using the numbering given in entry CAC16629.1 (GeneID 23095)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KIF1B Antibody

Immunoprecipitation: KIF1B Antibody [NB100-57494]

Immunoprecipitation: KIF1B Antibody [NB100-57494]

Immunoprecipitation: KIF1B Antibody [NB100-57494] - Detection of Human KIF1B by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-KIF1B antibody NB100-57494 used for IP at 3 mcg/mg lysate. KIF1B was also immunoprecipitated by rabbit anti-KIF1B antibody NB100-57493, which recognizes an upstream epitope. Detection: Chemiluminescence with an exposure time of 10 seconds.

Applications for KIF1B Antibody

Application
Recommended Usage

Immunoprecipitation

2 - 5 ug/mg lysate
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: KIF1B

The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. KIF1B is a member of the KIF1/Unc104 family of kinesin-like proteins that are involved in the transport of mitochondria or synaptic vesicles in axons. KIF1B is an amino-terminal-type motor protein that is ubiquitously expressed, with the most abundant levels in differentiated nerve cells. The human KIF1B gene maps to chromosome 1p36.2. Defects in axonal transport due to mutations at the KIF1B gene can underlie the human peripheral neuropathy phenotype. The mouse KIF1B gene generates an alternatively spliced transcript, which produces two isoforms, a 7.8 kb mRNA encoding a 130 kDa protein, and a 10 kb mRNA encoding a 204 kDa protein.

Alternate Names

CMT2, CMT2A, CMT2A1, HMSNII, KIAA0591FLJ23699, KIAA1448, kinesin family member 1B, kinesin superfamily protein KIF1B, kinesin-like protein KIF1B, KLP, MGC134844, NBLST1

Entrez Gene IDs

23095 (Human); 20395 (Mouse)

Gene Symbol

KIF1B

UniProt

CAC16629.1 (Human)

Additional KIF1B Products

Product Documents for KIF1B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KIF1B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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