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KIR2DS2 Antibody [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-82102JF525

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Janelia Fluor 525

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2. Amino Acid Squence: EPAGNRTVNSEDSDEQDH

Specificity

KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for KIR2DS2 Antibody [Janelia Fluor® 525]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: KIR2DS2

The KIR2DS2 gene encodes a 304 amino acid long, 33 kDA killer cell immunoglobulin-like receptor 2DS2. This receptor is for HLA-C alleles but it does not prevent any activity of NK cells. The KIR2DS2 gene participates in DAP12 interactions, the innate immune system as well as the adaptive immune system, as well as immunoregulatory interactions between a lymphoid and a non-lymphoid cell. It is known to interact with genes HLA-C and TYROBP. The KIR2DS2 gene is linked to ulcerative colitis, spondylitis, anterior uveitis, diabetes, hodgkin's lymphoma, lupus, psoriatic arthritis, birdshot chorioretinopathy, and vigt-kooyanagi-harada disease.

Long Name

Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 2

Alternate Names

183ActI, CD158b, CD158j, Cl-49, NKAT5, p58 NK Receptor CL-49

Gene Symbol

KIR2DS2

Additional KIR2DS2 Products

Product Documents for KIR2DS2 Antibody [Janelia Fluor® 525]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KIR2DS2 Antibody [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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