KIR3DL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31609

Novus Biologicals, part of Bio-Techne
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NBP1-31609
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse, Rat

Predicted:

Primate (90%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Frozen, Western Blot

Cited:

Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KIR3DL1 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human KIR3DL1. The exact sequence is proprietary.

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 26679227). Mouse reactivity reported in scientific literature (PMID: 24815059). Chimpanzee (90%).

Localization

Cell membrane, Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for KIR3DL1 Antibody

Western Blot: KIR3DL1 Antibody [NBP1-31609]

Western Blot: KIR3DL1 Antibody [NBP1-31609]

Western Blot: KIR3DL1 Antibody [NBP1-31609] - Sample(30 ug whole cell lysate)A:A431 B:H129910% SDS PAGE, antibody diluted at 1:1000.

Applications for KIR3DL1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Application Notes
IHC-Fr usage reported in scientific literature (PMID: 24815059).

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: KIR3DL1

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq]

Long Name

Killer Cell Immunoglobulin-like Receptor, Three Domain Long Cytoplasmic Tail, 1

Alternate Names

CD158e1, Nkat3, NKB1

Gene Symbol

KIR3DL1

Additional KIR3DL1 Products

Product Documents for KIR3DL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KIR3DL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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