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Klotho Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-2432

Novus Biologicals, part of Bio-Techne
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NB100-2432

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-KRDDAKYMYYLKK corresponding to internal region according to NP_004786.2, NP_710150.1.

Specificity

This antibody is expected to recognise both reported isoforms (NP_004786.2; NP_710150.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Klotho Antibody

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432] - Staining of Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432]

Immunohistochemistry-Paraffin: Klotho Antibody [NB100-2432] - Staining of Human Breast. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Applications for Klotho Antibody

Application
Recommended Usage

Immunohistochemistry

4 - 6 ug/ml

Immunohistochemistry-Paraffin

4 - 6 ug/ml

Peptide ELISA

Detection limit 1:4000
Application Notes
WB: Preliminary experiments in human brain, duodenum, placenta and prostate lysates gave no specific signal but low background. IHC-P: Human breast shows cytoplasm staining in luminal epithelial cells of ducts, while human placenta shows membranous staining.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Klotho

The Klotho gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (

Alternate Names

KL

Entrez Gene IDs

9365 (Human)

Gene Symbol

KL

UniProt

Additional Klotho Products

Product Documents for Klotho Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Klotho Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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