Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all KLRA1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human KLRA1. The immunogen is located within amino acids 190 - 240 of KLRA1. Amino Acid Squence: IGLSYDERESKWK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KLRA1 Antibody - BSA Free

Western Blot: KLRA1 AntibodyBSA Free [NBP1-76983]

Western Blot: KLRA1 AntibodyBSA Free [NBP1-76983]

Western Blot: KLRA1 Antibody [NBP1-76983] - 293 cell lysate with KLRA1 antibody at (A) 1 ug/ml and (B) 2 ug/ml.
KLRA1 Antibody - BSA Free

Immunohistochemistry: KLRA1 Antibody - BSA Free [NBP1-76983] -

Immunohistochemistry: KLRA1 Antibody - BSA Free [NBP1-76983] - Immunohistochemistry of KLRA1 in human spleen tissue with KLRA1 antibody at 2.5 ug/mL.
KLRA1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-76983] -

Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-76983] - Immunofluorescence of KLRA1 in Human Spleen cells with KLRA1 antibody at 20 ug/mL.

Applications for KLRA1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KLRA1

KLRA1 (also known and Ly49L) is a member of the LY49 family of receptors Natural killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist.

Alternate Names

killer cell lectin-like receptor subfamily A pseudogene 1, KLRA#, KLRA1, Ly49, LY49L, Ly-49L, MGC126520, MGC126522

Gene Symbol

KLRA1P

UniProt

EAW96194 (Human)

Additional KLRA1 Products

Product Documents for KLRA1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KLRA1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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