Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all KLRA1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 13 amino acid synthetic peptide near the center of human KLRA1. The immunogen is located within amino acids 140 - 190 of KLRA1. Amino Acid Squence: CYYFTMQKKDWKG

Specificity

At least three isoforms of KLRA1 are known to exist; this antibody recognizes only the long isoform.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KLRA1 Antibody - BSA Free

Western Blot: KLRA1 AntibodyBSA Free [NBP1-77343]

Western Blot: KLRA1 AntibodyBSA Free [NBP1-77343]

Western Blot: KLRA1 Antibody [NBP1-77343] - Mouse spleen tissue lysate with KLRA1 antibody at (A) 1 ug/ml and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343]

Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343]

Immunocytochemistry/Immunofluorescence: KLRA1 Antibody [NBP1-77343] - Immunofluorescence of KLRA1 in 293 cells with KLRA1 antibody at 20 ug/mL.
Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343]

Immunocytochemistry/ Immunofluorescence: KLRA1 Antibody - BSA Free [NBP1-77343]

Immunocytochemistry/Immunofluorescence: KLRA1 Antibody [NBP1-77343] - 293 cells with KLRA1 antibody at 4 ug/ml.
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Applications for KLRA1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

4-20 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KLRA1

KLRA1 (also known as Ly49L) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA1 is thought to be an activating receptor, inducing DAP12 phosphorylation in response to antibody-mediated cross-linking of KLRA1 on NK cells. At least three isoforms of KLRA1 are known to exist; this antibody recognizes only the long isoform.

Alternate Names

killer cell lectin-like receptor subfamily A pseudogene 1, KLRA#, KLRA1, Ly49, LY49L, Ly-49L, MGC126520, MGC126522

Gene Symbol

KLRA1P

UniProt

EAW96194 (Human)

Additional KLRA1 Products

Product Documents for KLRA1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for KLRA1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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