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KMT2D Antibody (CL5346)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61416

Novus Biologicals, part of Bio-Techne
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NBP2-61416
NBP2-61416-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL5346

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHI

Reactivity Notes

Expected species cross reactivity based on sequence identity: Rat (80%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for KMT2D Antibody (CL5346)

Immunocytochemistry/ Immunofluorescence: KMT2D Antibody (CL5346) [NBP2-61416]

Immunocytochemistry/ Immunofluorescence: KMT2D Antibody (CL5346) [NBP2-61416]

Immunocytochemistry/Immunofluorescence: KMT2D Antibody (CL5346) [NBP2-61416] - Staining of CACO-2 cells using the Anti-KMT2D monoclonal antibody, showing specific staining in the nucleoplasm and golgi apparatus in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available). Antibody staining is shown in green.

Applications for KMT2D Antibody (CL5346)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KMT2D

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription

Alternate Names

AAD10, ALRALL1-related protein, CAGL114, EC 2.1.1.43, histone-lysine N-methyltransferase MLL2, KMT2D, Lysine N-methyltransferase 2B, MLL4, myeloid/lymphoid or mixed-lineage leukemia 2, Myeloid/lymphoid or mixed-lineage leukemia protein 2, TNRC21, trinucleotide repeat containing 21

Gene Symbol

KMT2D

Additional KMT2D Products

Product Documents for KMT2D Antibody (CL5346)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KMT2D Antibody (CL5346)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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