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KNL-2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89905

Novus Biologicals, part of Bio-Techne
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NBP1-89905
NBP1-89905-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QHQRILLPSFQDSEDDDDILPNMDKNPTTPSSVIFPLVKTPQCQHVSPGMLGSINRNDCDKYVFRMQKYHKSNGGIVWGNIKKKLVETDFSTPTPRRKTPFNTDLGENSGIGKLFTNAVESLDE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KNL-2 Antibody

Immunocytochemistry/ Immunofluorescence: KNL-2 Antibody [NBP1-89905]

Immunocytochemistry/ Immunofluorescence: KNL-2 Antibody [NBP1-89905]

Immunocytochemistry/Immunofluorescence: KNL-2 Antibody [NBP1-89905] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoli & cytosol.
Immunohistochemistry-Paraffin: KNL-2 Antibody [NBP1-89905]

Immunohistochemistry-Paraffin: KNL-2 Antibody [NBP1-89905]

Immunohistochemistry-Paraffin: KNL-2 Antibody [NBP1-89905] - Staining of human spleen shows moderate nuclear positivity in cells in red and white pulp.

Applications for KNL-2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KNL-2

KNL-2 is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.

Alternate Names

C14orf106, chromosome 14 open reading frame 106, FLJ11186, hsKNL-2, KIAA1903HSA242977, Kinetochore-associated protein KNL-2 homolog, KNL2, M18BP1, MIS18 binding protein 1, mis18-binding protein 1, P243, putative protein p243 which interacts with transcription factor Sp1

Gene Symbol

MIS18BP1

Additional KNL-2 Products

Product Documents for KNL-2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for KNL-2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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