KPNA3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14172

Novus Biologicals, part of Bio-Techne
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NBP2-14172
NBP2-14172-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all KPNA3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DPCLIPEATQGGTYNFDPTANLQT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for KPNA3 Antibody

Western Blot: KPNA3 Antibody [NBP2-14172]

Western Blot: KPNA3 Antibody [NBP2-14172]

Western Blot: KPNA3 Antibody [NBP2-14172] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Immunocytochemistry/ Immunofluorescence: KPNA3 Antibody [NBP2-14172]

Immunocytochemistry/ Immunofluorescence: KPNA3 Antibody [NBP2-14172]

Immunocytochemistry/Immunofluorescence: KPNA3 Antibody [NBP2-14172] - Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: KPNA3 Antibody [NBP2-14172]

Immunohistochemistry-Paraffin: KPNA3 Antibody [NBP2-14172]

Immunohistochemistry-Paraffin: KPNA3 Antibody [NBP2-14172] - Staining of human heart muscle shows moderate nuclear positivity in myocytes.

Applications for KPNA3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: KPNA3

The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA3, encodes a protein similar to certain nuclear transport proteins of Xenopus and human. The predicted amino acid sequence shows similarity to Xenopus importin, yeast SRP1, and human RCH1 (KPNA2), respectively. The similarities among these proteins suggests that karyopherin alpha-3 may be involved in the nuclear transport system. [provided by RefSeq]

Alternate Names

hSRP1, importin alpha 4, Importin alpha Q2, importin alpha-3, importin subunit alpha-3, importin-alpha-Q2, IPOA4, karyopherin alpha 3 (importin alpha 4), Karyopherin subunit alpha-3, qip2, SRP1, SRP1gamma, SRP1-gamma, SRP4

Gene Symbol

KPNA3

Additional KPNA3 Products

Product Documents for KPNA3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for KPNA3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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