Kv7.2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-85193

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all Kv7.2 Antibodies »

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human Kv7.2. Peptide sequence: GNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Kv7.2 Antibody

Western Blot: Kv7.2 Antibody [NBP2-85193]

Western Blot: Kv7.2 Antibody [NBP2-85193]

Western Blot: Kv7.2 Antibody [NBP2-85193] - WB Suggested Anti-KCNQ2 Antibody Titration: 1.25ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate
Immunohistochemistry: Kv7.2 Antibody [NBP2-85193]

Immunohistochemistry: Kv7.2 Antibody [NBP2-85193]

Immunohistochemistry: Kv7.2 Antibody [NBP2-85193] - Human kidney
Western Blot: Kv7.2 Antibody [NBP2-85193]

Western Blot: Kv7.2 Antibody [NBP2-85193]

Western Blot: Kv7.2 Antibody [NBP2-85193] - Host: Mouse. Target Name: KCNQ2. Sample Tissue: Mouse Skeletal Muscle. Antibody Dilution: 1ug/ml

Applications for Kv7.2 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Kv7.2

KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M current. Inhibition of M current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.

Long Name

Potassium voltage-gated channel subfamily KQT member 2

Alternate Names

KCNQ2, KQT-like 2

Gene Symbol

KCNQ2

Additional Kv7.2 Products

Product Documents for Kv7.2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Kv7.2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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