L1CAM Antibody (CL12988)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-18553

Novus Biologicals, part of Bio-Techne
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NBP3-18553-100ul
NBP3-18553-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL12988

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all L1CAM Antibodies »

Product Summary for L1CAM Antibody (CL12988)

Immunogen

This antibody was developed against a sythetic peptide for P32004. Actual immunogen sequence is proprietary.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for L1CAM Antibody (CL12988)

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553] - Staining of human kidney shows strong membranous positivity in a subset of cells in tubules.
Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553] - Analysis in human cerebral cortex and testis tissues using NBP3-18553 antibody. Corresponding L1CAM RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553]

Immunohistochemistry-Paraffin: L1CAM Antibody (CL12988) [NBP3-18553] - Staining of human ovarian cancer (clear cell carcinoma) shows moderate membranous positivity in a subset of tumor cells.
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Applications for L1CAM Antibody (CL12988)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For use with IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: L1CAM

The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Long Name

Cell Adhesion Molecule L1

Alternate Names

CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1

Gene Symbol

L1CAM

Additional L1CAM Products

Product Documents for L1CAM Antibody (CL12988)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for L1CAM Antibody (CL12988)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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