L1CAM Antibody (L1CAM/9267R)
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23698
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Recombinant Monoclonal Rabbit IgG Kappa Clone # L1CAM/9267R
Concentration
0.2 mg/ml
Product Specifications
Immunogen
Recombinant fragment (around aa600-900) of human L1CAM protein (exact sequence is proprietary)
Localization
Cytoplasm. Cell Surface.
Specificity
This mouse monoclonal antibody recognizes the sequence immediately NH2-terminal to the tyrosine-based motif and binds L1 only when Y1176 is dephosphorylated. Phosphorylation of either T1172 or Y1176 strongly inhibits binding of 74-5H7 to the L1 cytoplasmic domain.
Clonality
Monoclonal
Host
Rabbit
Isotype
IgG Kappa
Description
Store at 2 to 8C. Non-hazardous. No MSDS required.
Applications for L1CAM Antibody (L1CAM/9267R)
Application
Recommended Usage
Immunohistochemistry-Paraffin
1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
10mM PBS with 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.2 mg/ml
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C.
Background: L1CAM
Long Name
Cell Adhesion Molecule L1
Alternate Names
CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1
Gene Symbol
L1CAM
Additional L1CAM Products
Product Documents for L1CAM Antibody (L1CAM/9267R)
Product Specific Notices for L1CAM Antibody (L1CAM/9267R)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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