L2HGDH Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49445

Novus Biologicals, part of Bio-Techne
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NBP2-49445
NBP2-49445-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all L2HGDH Antibodies »

Product Summary for L2HGDH Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KKEPYCRGLMAIDCPHTGIVDYRQVALSFAQDFQEAGGSVLTNFEVKGIEMAKESPSRSIDGMQYPIVIKNTKGEEI

Reactivity Notes

Mouse (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for L2HGDH Antibody

Immunocytochemistry/ Immunofluorescence: L2HGDH Antibody [NBP2-49445]

Immunocytochemistry/ Immunofluorescence: L2HGDH Antibody [NBP2-49445]

Immunocytochemistry/Immunofluorescence: L2HGDH Antibody [NBP2-49445] - Immunofluorescent staining of human cell line MCF7 shows localization to mitochondria.
Immunohistochemistry-Paraffin: L2HGDH Antibody [NBP2-49445]

Immunohistochemistry-Paraffin: L2HGDH Antibody [NBP2-49445]

Immunohistochemistry-Paraffin: L2HGDH Antibody [NBP2-49445] - Staining of human duodenum shows strong positivity with a granular a pattern in glandular cells.

Applications for L2HGDH Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: L2HGDH

The L2HGDH gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive

Alternate Names

2-hydroxyglutarate dehydrogenase, alpha-ketoglutarate reductase, C14orf160alpha-hydroxyglutarate oxidoreductase, chromosome 14 open reading frame 160, Duranin, EC 1.1.99.2, FLJ12618, L-2-hydroxyglutarate dehydrogenase, L-2-hydroxyglutarate dehydrogenase, mitochondrial, L-alpha-hydroxyglutarate dehydrogenase

Gene Symbol

L2HGDH

Additional L2HGDH Products

Product Documents for L2HGDH Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for L2HGDH Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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